I was prescribed prednisone (prednisone burst) for my endolymphatic hydrops (inner ear disorder). My initial dose was 80 mg for 4 days and then tapered down over the next 2 weeks. I took my last 5 mg today. I to have experienced the mood swings, along with extra energy, anxiety, fatigue, stiff neck muscles, sore leg muscles, weak leg muscles, nausea, sweaty palms and feet. I decided to go on prednisone after my doctor said it would help rule out autoimmune disease. I will never go on this drug again unless it is life threatening situation. It is a very nasty drug and my family has had to live with me during this difficult time. I'm leaving my condition up to the Great Physician!