I've just started taking sertraline a couple months ago, I've worked up from 25mg to 100mg, and I see a bit of difference in my mood levels. The best way I can describe it is that my low points aren't as low as they used to be and my general level of anxiety has eased. I just recently changed over to the 100mg dosage a couple days ago and I'm feeling what I hope to be the initial numbness, which I hope will go away soon. One thing that is fairly concerning is that I havent' been able to cry since I started on this medication. I'm usually prone to crying jags during low points and within the last couple of months I havent' had one or had the urge to have one.
I think it's from my inability to stay concentrated on a single subject for a period of time, like others mentioned, I've noticed that I zoloft has decreased my attention level. Eh, but I"m not sure if the fact that I can't cry is a good or bad thing, we'll see how everything turns out once my dosage is stabilized.