I am on my 5th pack of Loestrin 24. This is my first time on birth control. I was worried about weight gain b/c a lot of my friends on various pill have gained a bit. But I, however, have lost about 10 pounds since starting Loestrin. I have been very sick to my stomach and have had no appetite. My periods have been very irregular and have yet to have a period on the brown pills. I notice that I have been fatigued and moody. I went to the doctor and asked if this was normal. He gave the typical response..."there is no normal. Everyone reacts differently" speech. So he scheduled me for a ultrasound and blood-work to see if there is an underlying problem before we decide to go pill hopping. This isn't fun, but the other option ( ie an unwanted pregnancy ) is really not fun.