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In the past five years I've gone through two six month Lupron tre...

Posted at 12:41 AM on Sep 15, 2008 by jackie_vandyke, #34496
In the past five years I've gone through two six month Lupron treatments. The first Lupron treatment was given without a Laparoscopy. After being told for ten years that I was one of the unlucky few who have "bad periods", I finally found a doctor who would listen. She diagnosed Endometriosis after I listed my symptoms and put me on a Lupron treatment plan. I had one one-month injection and two three-month injections. Most of my side effects were tolerable; weight loss (almost sixty pounds but I was over weight to begin with), hot flashes, night sweats and memory loss. However, I experienced horrible back and hip pain...to the point of following up with a pain management doctor who insisted there was no reason for me to be in pain. About four years later I found a really great doctor who performed a laparoscopy to diagnose my endo. She removed fibroid tissue from both ovaries and my colon. My next period was just a horrible so she suggested we follow up with another Lupron cycle. I expressed my concerns with the pain I experienced the first time and she suggested I have add-back therapy. She prescribed a regimen of Estradiol and Norethindrone along with six monthly Lupron injections. The side effects were worse this time around. My depression kicked into overdrive, I was constantly struggling to keep my anger in check, I would wake up dripping from night sweats, hot flashes were bad, blurred vision, memory loss, insomnia and the pain in my back and hips was excruciating. She prescribed Celebrex for my back and hip pain, which didn't help too much. I have a three year old son and had to use a wheel chair when we went to the museum because being on my feet for more than fifteen minutes was impossible. I've now been off the Lupron for about six months and I have yet to regain any sort of short term memory. My vision is much worse than before I started the second cycle and has yet to reverse. My depression is still bad, as well as anxiety and irritability. However, as soon as the last month of Lupron started to wear off, my back pain did dissipate. I'm still having trouble sleeping but have found solace in Ambien...which could be a bad thing. I don't want to depend on chemicals to help me sleep at night. I just had my yearly exam with my doctor and she apologized for all the pain I experienced. She told me that in all the years she's given Lupron treatments, she had never seen a patient in as much pain as I was in. I don't think I'll be undergoing the Lupron treatments again in the future. I'm currently starting Yaz as a way to keep my periods at bay and only have three or four a year. I'm not real sure if that's a good thing either but we'll see. I have sympathy for all the other Lupron patients out there who experience the bad side of the drug. I don't understand how a medication such as this, which has such drastic side effects, can be marketed to people who are already suffering from pain in the first place.
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Reply about 1 year ago on Oct 05, 2008 by hollycalcote, #13149

I've done the Yaz as well and I felt crazier on Yaz then on the Lupron shots. I wouldn't suggest it. I have been dealing with this for 8 years now and have had 6 laporoscopies, don't do yaz.

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Reply about 1 year ago on Oct 24, 2008 by lindsey23, #13785

I wouldn't suggest skipping periods. I too suffered depression, anxiety and and memory loss during and after Lupron injections. Then they put me on birth control where you only have periods every 3 months....bad idea! I felt like I was on lupron all over again.

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Reply about 1 year ago on Nov 04, 2008 by 3surgeries2many, #14148

I am going tomorrow for my second Lupron shot. So far in a month the abdominal pain has decreased a bit but I am having severe lower back pain and bad side aches. I have started experiencing the hot flashes and can't sleep very well at night. My doctor has told me numerous times that I have been his worst case Endometriosis. I have had 3 surgeries because of my endo and now the only option I have left is the Lupron for pain. My question is, is the side effects worse than the endo pain? Please contact me.

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