Well, I have just started taking Doxy for a couple of days now and so far have noticed a change in bowel movements, appetite, a bit of nausea, my stomach has been feeling a bit bubbly and weird here and there. Also, it makes me feel high after taking it. And i know this sound funny but it makes my bottom itchy. Which is all really weird but over all I don't really care about the side effects as long as they dont become too extreme. I think as long as I take the medicine on terms that are best for me I will be just fine. I am just very glad to be getting rid of an infection that was causing me a lot more pain and discomfort than this med and will be glad when this is over. The biggest issue I have with the pills is getting them down my throat...I'm not a good pill taker and they make me gag. I can't imagine having to take them and deal with side effects for months at a time as some of you are doing so good luck to everyone!! And I also agree that doctors really do need to address the more serious side effects on this med! After coming to this site I will definitely take precautions.