I was taking Doxy. Hyclate for 3 days prior to a breakout of an allergic reaction. Initially, the small bumps resembled flea bites or could even be mistaken for pimples; however, they later manifested into blisters onto my legs and arms. As with other (skin) allergic reactions, the bumps were red and itchy. I immediately notified my physician and began using hydrocortisone cream and benadryl to minimize the discomfort.