I had a cold/sinus infection for almost three weeks, so I went to the doctor on Tuesday and he put me on the z-pak. That night I woke up at 4 am with a server ear infection and drove myself to the ER. They put me on Cipro and ear drops..well the next day I woke up feeling even worse and had laryngitis and it burned to breathe, so on Friday morning I went back to my general doctor and he took me off the cipro and prescribed me AVELOX. I took it this morning (Saturday) and within 15 minutes I had a really itchy throat, and my upper lip started tingling. I had panic attacks, was gasping for air and by the time I left for the ER my entire face had swelled, and my eyes were swelling shut. The put me on an IV drip steroid & IV pepcid, waited till my swelling went down & sent me home with prednisone & pepcid for the next 4 days, and said just to finish off my zpak. The scary thing is that this happened within 15 minutes of my first dose..I think this is a terrible drug! I should have just stayed on the z-pak to begin with!