My daughter is no longer on advair, but when she was I thought she was a hypochondriac. She had asthma since age 3 and by the time she was in 4th grade she was put on advair. She gained weight in her face and stomach. She would have trouble concentrating on her school work, stayed moody. She would lash out for little or no reason. She always had some ache or pain. Almost every day either her head hurt or her stomach hurt. It was would last under an hour each time
She started having muscle pains. had to be in a walking cast twice for soft tissue damage to her ankle. She would have no idea how it got hurt. If she crawled on her knees playing she would get fluid on her knees. She would have knee pain off and on for a weeks at a time. All the time we were at one doctor or another. Every one of them said her asthma medicine would not cause this. The last straw was when in 6th grade her shoulders would pop out of place if she tried to do push ups in gym. She had to have physical therapy three times a week for three months. Even though the doctors told me not to she has been off of advair for 4 years now. All of the side effects went away with the except for the problems with her shoulders. She has to do exercises a few time a week to keep the muscle's strong to hold them in place.