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I just started taking the generic Wellbutrin SL 150mg last month....

Posted at 2:49 PM on Sep 29, 2008 by hmattingly, #35098
I just started taking the generic Wellbutrin SL 150mg last month. I was on generic Zoloft and felt like it had not been working for a few years (well, actually not working since I went on the generic form due to the high cost of the name brand.) My dr. told me to wean off Zoloft (cut pill in half) for a week while taking Wellbutrin. After the first week of this, I was scared. My heart was racing, I was out of breath just climbing the stairs (which I do a lot every day holding a baby...never a problem before), hot flashes, dizziness, a heart burn feeling in my chest, etc. I called my dr. back and she said to continue taking Zoloft for another week. I felt better once I began it again. I gave myself another week taking both drugs and then stopped Zoloft for the last time. Since then, I have had horrible mood swings with bursts of anger and constant crying fits. I rarely feel good and am waiting for the energy to come that I read in other people's postings. Instead of energy, I am experiencing severe tiredness. I have just been tested for Celiac disease, which could explain the tiredness, mood swings, etc., but not to the extent of what I am currently experiencing. Since being on Wellbutrin, I feel like I am in a nightmare. My husband and kids don't know what to expect from me day-to-day. I want to get off this drug, but know I need to be on something This one works well for my brother, so I thought I would give it a try. I'm ready to go back on Zoloft and forget trying to find something that works better for me. I can't handle the mood swings and crying. At least with Zoloft, I was more mellow - just no energy.
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Reply 17 days ago on Nov 18, 2008 by oceancat, #14601

There's no reason why you can't take your regular Zoloft with the Wellbutrin. To put it in basic terms, probably the calming serotonin in Zoloft is needed to balance the energizing effects of the norepinephrine and dopamine in Wellbutrin. The Zoloft + Wellbutrin combo is used often -- just have your doctor pick the doses he or she thinks would be best for you to create the optimum balance. I use this combination myself, and it works very well.

Good luck!

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