I had been on Effexor for about three years and could no longer stand the side effects so doc put me on Cymbalta. Wonder drug to start with. I felt happy, normal. After two weeks on 30mg per day the doc increased the dose to 60mg per day. SHEER HELL! It started with a mild pain in my left foot and after a week at 60mg both my feet were swollen with intense burning and incredible pain. Went off the meds and four weeks later I am still in intense pain and my feet feel permanently on fire. Anti-inflammatories only take the edge off the pain but not the burning