I had a sinus infection and my doctor handed me samples of Levaquin, 5 doses at 750mg each. I took it for the first 2 days, couldn't sleep, forgot to take it on the 3rd day because I finally was able to catch up on the sleep that I missed from the 1st and 2nd day. Took the third dose and noticed that my shoulder (left shoulder) was starting to hurt, I thought I had slept on it the wrong way, until I started looking at the side effects on the 4th day after I took my 4th dose. After I read the side effects I threw the 5th dose in the trash. I love my doctor and he has always helped by giving out samples, but what the samples don't tell you are the side effects. Needless to say I have been off of it for 2 days now. I am sleeping slightly better, but now have to adjust the way I sleep because I can't raise my arm any higher than level to my shoulder with out horrible pain. I am 28 and very active but now I fear that I may have to worry about rupturing my shoulder. I think I will head back to my doctor to see what I can do.