So thankful I found this website and that I am not the only one having these problems! I started the NR this past February and thought it would be great not to have to worry about taking the pill. I had been taking Kariva and besides it being a pain to worry about, I also started gaining wt for the first time since high school (it had been two years with no wt gain). A few months ago I started working with a personal trainer and running to prepare for a 1/2 marathon...after three months I am now up 7 lbs even with working out 6 days a week! I assume it is severely causing me to retain fluid. I have not noticed mood changes but definitely no sex drive. I used to get migraines all the time and those are actually gone. The biggest side effect I have noticed which no one else has mentioned is heart problems. I have always worked out and ran a lot in high school with no previous problems. When I began training for my 1/2 marathon I noticed I was SOB, fatigued, and having palpitations all the time. Running for long periods of time has been impossible. I never thought it could be the NR until the last few days. It is the only thing I have done different. If I weren't married I would quit bc all together but instead I plan on going back to Ortho Tri-Cyclen Lo which I had the best results from.