I took Advair for almost 4 years. I did not take it regularly (as regularly as they prescribed), but took it reasonably regularly.
I think Advair is the worst drug! It wrecked my teeth! I had perfect (no cavities) until I started taking Advair, which is when I started getting cavities. My teeth will never be the same.
The worst part though, was that after about 2 years of use, I got a horrible case of pleurisy. I had it for 8 months. I went to dr. after dr. No one would listen. I finally got one to do a lung x-ray--within which I had scaring throughout my chest/bronchial tubes. My asthma was getting horrible, and I was literally at 75% oxygen intake (yah--my asthma dr. later told me I should have been in the hospital). I finally looked up and researched Advair--and found out that one of it's side effects was lung infections. By the time I found this out, I basically had a lung infection for 2 years. I fought with my asthma dr.--to get off of Advair. Put me on Flovent instead, which has been fine. I was off and on Prednisone for more than a year throughout all this time. Once off of Advair, the dr. put me on a regular dose of Prednisone (probably gained 15-25 pounds during that time), and an anti-biotic, once I finally won that battle. I FINALLY got better after about a month of treatment! But, ever since then I cannot get a cold/upper respiratory infection without having to go on prednisone in order to stop the cough. Plus, I then got my gall bladder out, and I now get major pain in that area when I get a cough.
I flat out refuse to EVER take Advair again. Nothing is worth going through anything like that again! It was miserable! I'm sure I had some other symptoms, such as stomach pains, headaches, depression, anxiety, etc., but seriously, I was just trying to breathe for so long, that none of the other stuff caused me as much worry!