I too have been injected previously with Kenalog shots for allergies. I never had the site indentation that most of you are commenting on. But I can tell you that the menstrual cycles did change considerably. Kenalog is a steroid, and like oral prednisone it is hormonal. It is just like taking birth control pills, you have the irregular or heavy periods, the excessive hunger, hair growth where you don't want it and weight gain. And as far as my allergies are concerned it never worked. I have excessive sinus disease that has been aggravated by living in a dry windy desert climate. After my second sinus surgery in 2 months the holes in my sinus cavity are starting to close up again. So yesterday my doctor tried a new therapy of injecting kenalog right into my sinus cavity. However it was not injected directly. A small piece of spongy foam was placed into my sinus cavity and the medicine was injected into the foam so my nose would absorb it naturally without the tissue being directly injected. I don't know if it will work or not. I have experienced some unpleasant side effects already, higher blood pressure and increased heart rate. Although the heart rate did come down after a few hours. Any kind of steroid causes this problem. I was hospitalized in January with a severe asthma attack and was given steroids thru a I.V. It was the only drug that opened up my lungs, however by the second day my heart temporarily went into v-tach because I was getting too much too often. As soon as it decreased I was fine. So dosage is a major concern. I can tell you from experience that Kenalog last realistically for about a month even though docs tell you it's good for 3. I would not have multiple injections for any reason. But when you are in pain and hurting and you have inflammation in your body, unfortunately steroids of some kind will always be the drug of choice. I have recently started acupuncture and will see if that helps my sinus problems. I have taken up yoga too to help my breathing. I highly recommend these alternatives to drug therapy. I have been on every kind of asthma and allergy drug out there and I do not trust any of them anymore. But ask the doctor lots of questions and refuse the meds if you are not comfortable. if your doctor is herding you in and out of his office or not willing to explain the meds completely then refuse it and go to someone else.