I have chronic migraine headaches and I was first prescribed Imitrex. All 4 times I gave it a chance it did not work. Since then, I have been prescribed 1 other migraine medicine which didn't work, a barbiturate to be taken just for headaches, which didn't work for the headache but made me very loopy then depressed, then a strong pain pill that did nothing for my headache but made me very relaxed, so I just layed on the bed for 4 hours. My doctor wanted me to get an MRI then go to a specialist who wanted to prescribe a medication that I would have to take 5 days a week. Now, I get kelation therapy once a month, which gets rid of high levels of metals and toxins in your body, and I have not had a bad migraine since, only a slight headache every once in a while.