i had a headache so i took the only thing that we had in our house which was acetaminophen/aspirin/caffeine. i had noticed before that when i had taken this medicine before that i had stomach upset for a little while and a feeling of shakiness, kinda like a weak feeling like i was out of it. i believe that this may be due to the caffeine in it. i do not have a huge caffeine intake daily, so i believe that is what causes the shaky feeling. i took the 2 pills with the water and i had a donut to eat after i took the pills, but i don't think that i had enough in my stomach to compensate for the strength of the pills. i started to have the stomach upset about 45 min to an hour after i took the pill. it seems to be slowly going away and i am thinking about going and getting something to eat to hopefully help the situation.