I agree that this drug is of evil. My mother was treated for 3 years on and off long term use for Wegener's Disease. She just tapered off her last dose, the docs are telling her she is done with it, thank the good Lord. She has told her doctor of all of her symptoms, manic episodes, severe depression, hallucinations and just recently the doctor suggested that it "may" be steroid psychosis. My mother inquired if there was some meds that could help b/c over time, it just seemed to get worse. She told her that she wasn't getting enough prednisone to cause this. Wasn't getting enough...when she was first diagnosed, she was given 3000 mg b/c she was near death, after that, each follow-up consisted of 40 plus mg, and I am talking 2 to 3 month stretches...but she wasn't getting enough to cause steroid psychosis??? My mother came to me one day and asked me not to leave my 3 year old daughter with her alone ever and of course I asked why. She told me that she had thoughts of harming those around her, that they would actually play out in her head. Through my tears, I asked my mother if she followed through with these thoughts, would that give her some relief, and she replied yes. At this point, I know it is bad. I have found a site that lists treatments for steroid psychosis and plan on not stopping until a physician agrees to help us. My prayers are with everyone that is experiencing these horrible drug interactions and side effects.