I was diagnosed with Endometriosis in March 2002 and a few months later started taking Lupron. My doctor wanted me to take it for 6months, but after the 3rd month, I could no long take the side effects. Before starting Lupron, I had the endo pains, but was pretty much healthy. After starting the Lupron injections, the pain did not improve, only worsened. I had unbareable hotflashes all day and night long. I still have them from time to time and I am only 19. I also have migraines (which I never really had before Lupron). And to top it all off, my immune system is so bad that if I am around anyone that is sick, I will get sick also --no question. Of course, I'm not able to prove that any of this is from the Lupron itself. And I know that it has helped others. But I wish someone would of better informed me before I started the treatments. The doctor only told me that it would put me into a chemical form of menopause and would make me pain free. I just want anyone who is thinking about starting Lupron therapy to really consider all of the risks before doing so. If you really feel its something that you need, then far be me to try to tell you not to do so. But definitely research it as much as you can, as doctors are most likely to tell you only the good aspects (since they are only making money in the long run).