I was diagnosed with ulcerative colitis in 2003, have been treated with Asacol ever since, and was in remission for nearly 5 years. I flared in December of 2007, and had my first experience with prednisone; I was on 40 mg/day for nearly 6 months. I gained 35 pounds, got the moon face, double-chin, tummy fat, muscle aches, extreme mood swings, excruciating headaches, night sweats, and UNCONTROLLABLE hunger. I, too, noticed the sensitive teeth, and now I feel like my enamel is really thin...almost see-through. Anyway, I've been off prednisone for about 5 months. The moon face went away for the most part, but my cheeks still seem a little chubbier than before, and my double-chin is a lot smaller, but still there. I've lost about half the weight, but only after joining weight watchers and working out 6 days a week. I feel like I can't lose any more weight to save my life. Does anyone have any suggestions? I never struggled with weight prior to taking this stupid drug. I'd appreciate any input.