Been taking the generic Clarithromycin for a little over 4 months now. I have Lyme Disease and this drug along with Plaquenil, really helps. With Lyme you feel worse before you can feel any inkling of feeling better Sure it's got some side effects like metallic taste and a few others. I will tell you for me the Lyme symptoms far outweigh the side effects, so I really don't mind the side effects at all. It's all relative. The metallic taste is one of the worst ones.
Of course you have to keep your gut in line with any antibiotic. Probiotics, yogurt, kefir, kombucha all help to do that.