Ive had really good results with this drug. Ive been happy alert cheerful etc.. like a "normal" person. I was taking it for about a year when Lithium was added to my cocktail and some very bad sexual side effects occurred. Thankfully a touch of real (im not going that here) Wellbutrin eliminated that but right now im off and in the wonderful land of generic budeprion. Im switching back to Effexor ASAP!!!