I have had chronic hives for a little over 5 months 24/7. I had taken Avelox for 10 days which was prescribed by my doctor for a upper respiratory infection. Although my infection had gone away, on my 10th day I woke up covered in hives head to toe. I went back to my family doctor that had prescribed Avelox to me and they injected a steroid shot in my hip. They were gone for 2 weeks, and then returned. For the past 5 months I have tried every treatment that my allergist has given me and nothing seems to work. I met another lady who had the same reaction from Avelox and she said her hives lasted for one year. I would not recommend taking this drug, because the side effect are not worth it.