I have been on Toprol XL 25 mg for a few years, then 50 mg for 2 years. The last two have been spent on 40 mg Benicar and 25 mg of Toprol XL. Originally I was put on to elevated heart rate, blood pressure, and palps at 24 years of age. I blame it on anxiety, especially the white coat kind, but have since gotten seem to get that control. Not to mention I have quit smoking, both cigs and pot, and cut down on the late nights of boozing from my twenties. In any case, I am still taking the Benicar to make sure my bp stays in control, but off the Toprol completely for a week now. I can feel my heart rate is more elevated at times, but I think that is good and actually natural. My energy has increased, especially while working out, and I am thinking clear for the first time in years. Not that I was stupid, I managed to get promoted twice and an MBA during my time on Toprol, but feel much better. Will see if I have any of the side effects from that everyone describes, but my experience both on and off the drug was pretty good. I think most people on this drug already have anxiety, so learning to control that is key to living a life off the drug. Good luck to everyone, but glad to be off at least one medicine.