Hi,
To the first poster: bbk I had the same problem. I've been on Adderall-the regular kind, not XR-since my ADD diagnosis in June.
Whenever I start an SSRI: Prozac, Zoloft, Effexor, Lexapro, my Adderall stops working. I get exhausted, brain fog, and I also get an insane appetite.
I've done some research and the explanations I've found are that SSRIs tend to increase your insulin and lower dopamine. Adderall is supposed to increase dopamine. Basically, the SSRI interferes with the Adderall.
In one appointment with my doctor (while I was on Prozac) he actually admitted that most SSRIs raise insulin, Prozac being worse than others. Guess that explains why my blood sugar was always in the 60s and I felt horrible no matter what I ate or did.
If you're already overweight and insulin resistant it will screw you up more than other people.
I'm currently trying to find an anti-depressant that works well with Adderall.