I have been through 5 cycles of IVF treatments all taking Lupron shots. The last cycle was 3 years ago. Lately, within the past 1-2 years, I have been very forgetful with names, forgetting where I'm driving to, in the middle of conversations, etc. And I also have knee pain but I'm not sure if maybe that is a result of working out too much at the gym. I am concerned with the constant forgetfulness and possible other side effects as I get older. I am now 42. While I was taking Lupron all that time, I have to say that I felt pretty good, aside from the small headaches from time to time. It basically stops your cycle. I do feel bad for those women who have had worse side effects. And I do question whether it ever leaves your body and if other side effects could be brain tumors (I heard that somewhere). Any insight would be appreciated. Good luck to all.