I began taking Lupron after I was diagnosed with endometriosis last November. For the first six months, the side effects were minimal. I never had hot flashes and didn't really notice a change in my body. The last six months on the drug I noticed significant differences. My hair started to fall out in clumps and I had trouble concentrating. This past October I had a total hysterectomy because the Lupron was not working. Today I feel like an 80 year old woman. I can't concentrate, my brain is in a constant fog, and I feel like I have Altzheimers. I can't remember anything and it is a major inconvenience. I have suffered from depression for most of my life. However, I believe this drug has worsened it to some extent. All day long, constantly I am battling negative thoughts. I have constant reminders of every little thing I've ever done wrong in my entire life. Recently I've started hearing whispers like I did when I suffered from post-partum depression. I've also been getting headaches every day but I don't know if these are related or not.
It would appear that I'm going to have to seek out a professional to deal with the voices. This is a side effect that I was not expecting, especially not after several months of not being on the shot anymore. The thing that bothers me is that I took the shot every three months for a year. It did nothing for me and I had a hysterectomy anyway. This is something to consider if you are debating whether or not to have the injection.