So I just finished a 10 day supply (20 pills) of this stuff. I was prescribed Biaxin twice a day for 10 days to clear up a minor sinus infection. I had no idea that this stuff caused so many issues, but now I know first hand. This medicine gave me pretty bad insomnia. I could fall asleep but would wake up at 2am/3am in the morning and couldn't fall back asleep. Of course lack of sleep, then gave me anxiety and minor depression like I've never had before. I will never take this stuff again. Not to mention, the bad taste that's in your mouth constantly. In retrospect, I'll take a sinus infection anyday over the side effects of this medicine. Maybe it's okay for some people, but I'll never put Biaxin in my body every again. I took my last dose yesterday evening and I've been drinking tons of water ever since to try and get rid of this stuff as soon as possible.