I am on Prednisone for the second year(5mg) 48 pack. My back hurts so bad I can not stand for long and walking is painful as well. This also happened last year too I thought my back was out of line because of the hospital bed, however I am starting to rethink it. I have had my back adjusted and it is just as painful. The body swelling and tiredness is unbelievable too. I think the doctor, are going wild in prescribing this horrible pill.