I was diagnosed with seven fibroids, with some the size of a golf ball. My doctor was talking about a hysterectomy, I'm 52, but I opted instead for Lupron. Before I couldn't bend over and had a lot of pain in my stomach. I am going on my third shot, and yes, I have gained weight. And I am tired a lot, but these small side effects are nothing compared to the pain i was in before. I am also taking a give back hormone pill that helps with the bone loss and mood swings. I have not had any of the other problems that others seems to have. I am hoping this will shrink them so no surgery is necessary.