I was switched from Armour to Synthroid and Cytomel and have experienced many problems. Severe heat intolerance, weight gain, sweating, heart palps were terrible. Also, my calves ache every day and have depression again. Didn't know which med was causing the severe sweating and heat & exercise intolerance so have been off Cytomel for 2 days and already the heat intolerance is better today. I miss the Armour and will be going back on it very soon.