I have been on Lamictal for 8 years and take 200mg every night. I take it in combination with Lithium, Seroquel, & Wellbutrin. My diagnosis is rapid cycling bi-polar. There was also Depakote for about 12 years but that's gone, thank God. The Lamictal, combined with the Seroquel, can knock me on my butt, I feel like a drunk. I stagger and my speech is slurred, and I am very sleepy. I have dry skin in my ears that never resolves and that is itchy & painful. I have bowel issues. I also have vivid dreams but not violent ones. No sex drive but I'm single so that's not a problem. I also need a nap every day. I'm sure that there are others but it's hard to tell because of the other drugs I take. Glad that I'm not the only one with issues.