This spray has saved my marriage. I only use it once in each nostril at bed time and it is enough relief to get me through the night without struggling to breathe and waking up my light-sleeping husband. As it says to only use for 3 days, I had some concern about side effects and dependency, but after almost 3 weeks of this once a day dosing, I have no complaints to report. I still haven't shaken my sinus infection, but it is much abated and I continue to use alcohol and neti pots to rinse and moisture my sinuses. One of my biggest downfalls is my failure to consume enough fluids, which exacerbates the sinus infections. I work at it, but it is hard for me to drink when I am not thirsty.