About every 2 years I'd get a kenalog shot to wipe out the eczema I had on my hands. I never had an adverse side effect that I can think of.
An alternate remedy is to use "DOMEBORO" solution. You can find it at any drug store. It comes in packets in a box. It is a powder that you mix with water and can either soak your hands in it or use a washcloth soaked in it and resting it on the affected area. It truly is a miracle - it immediately relieves the itch and aggravation of the pain. It costs about $14.99 for the box.