My experience with Lisinopril has been awful. Severe headaches, Bad chest pains to where I thought I was having a heart attack, Severe depression. Didn't even want to get dressed and face my day. Shortness of breath and fatigue. The headaches were the worse. Felt like my eyes were going to burst out of my head. I couldn't think straight. The fatigue was so bad I found myself falling asleep while driving. I took myself off this medicine one day and I feel like a new person.