i have actually been on effexor for 3 years i have no appetite but have never lost any weight , i cannot sleep at nights i was up until 7 clock this morning i did not realize how many side effects there are and i am lucky that my doctor is taking me off them and putting me on a different tablet, the first night i cut down on my effexor and took the other ones i slept for the first time all night however that only lasted one night and i have been up every night since then , i am on a lower dose of effexor but i quess it will be some time before i will see the results , it has completly changed my life as i sometimes sleep all day i feel like i have some kind of sleeping sickness through the day as i cannot stay awake , i was told to take effexor at night so it is no wonder i could not sleep , i am suffering extreme pain every day not due to the effexor at least i dont think it is i am no morphine sulphate tablets and medicine i feel like a walking wreck i am not sure how much it is due to the effexor as i am on so many tablets it would be hard to say it was that alone. i itch all day long and i do not feel i have had any benifit at all from the effexor tablets