I'd had been on Altace 20mg (2-10mg capsules) for about 2 yrs. A year ago a 25mg. HCTZ tablet was added. BP was under control (140-150s/ 80's) with only side effects from HCTZ, cramping from mineral imbalance, and the occasional bouts of being lightheaded. I decided to go off meds and monitor BP. I was fine for about 6 weeks, but then BP started up and felt I needed to get back on meds. Dr. agreed and prescribed what she said was a replacement ACE inhibitor with the convenience of HCTZ built in, Lisinopril HCTZ. She also prescribed Benicar an ARB. I took both for five days with side effects of being light-headed, feeling like fainting occasionally. On day 6, I developed an ugly skin rash/swelling on right front part of my head. I thought it might big a spider bite. Next day I developed more of the same on the right side of my nose, my right eye, and on my right cheek. I thought it was the Benicar, since I was made to believe an ACE inhibitor is an ACE inhibitor (from Altace to Lisinopril), and did not have a history of problems with it, and the ARB was the new kid on the block. I quit taking the Benicar but the symptoms persisted for 3 more days. I called the Dr. and was told they did not believe it was related to the meds since it did not manifest earlier, but to go ahead and stop taking the Benicar until the symptoms subsided, then resume to see if they came back ( sound like good advice to you?) 4 days after being off Benicar the rashes and swelling were worse. I then decided the problem had to be the Lisinopril. I have been off only 24 hrs, but symptoms are starting to improve. I will be calling tomorrow for a new Dr.