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45 years old, female, diagnosed bipolar II in 2006. On Lamictal f...

Posted at 3: 4 PM on Jan 27, 2009 by siri, #38412
45 years old, female, diagnosed bipolar II in 2006. On Lamictal for 2 years. Initially, very positive effects of Lamictal - felt "normal" and stable for the first time in years. Didn't notice any side effects. Gradually increased from 200 to 400 mg per day 6 months ago as I still experienced mood swings with a tendency towards depression. I have been on 400 mg/day since August 2008. It is difficult to say what are the side effects of the medication, and what are "natural causes". Since doubling the dosage, I experience memory loss and increasing cognitive problems (slow thought process, difficulty putting together coherent sentences in discussions, fumbling for words. I have spent more than one hour on this posting!). I sometimes wake up during the night drenched in sweat. It could be that I'm menopausal, but I find it unlikely. Mood swings have perhaps become less pronounced, but I would like to regain my mental capacity. I plan to cut back to 200 mg of Lamictal - and perhaps some day learn to live with bilpolar II without medication and a lot of help from my friends and loved ones.
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Reply 8 months ago on Mar 06, 2009 by jberkenbile, #17751

I am also 45 and have had 3 seizures since June. I found out that a persons level of lamictal in their system is greatly impacted by their period. It has been over 13 weeks since my last period and that isn't good either. You jokingly mentioned menopause but it does have something to do with what you are experiencing. I had started taking a product to counter my mood swings I get from my period. During my period I had a seizure. I immediately quit taking what I was using and poof no more problems. My periods are awful and usually come every 23 days. I talked to my GYN and asked if I could take the pill to help regulate my period. He said yes. After taking it 6 days, I had a seizure. That is when I found out that the lamictal can be compromised by oral contraceptives. I quit taking them and no problem. In my infinite wisdom, I thought I would take a menopause supplement to help counter mood swings and hot flashes. I took it for about 3 months. I didn't have a period that entire time (YAHOO) and all of a sudden had a seizure. My neurologist seems to think each incident can be tied to what I was taking that was designed to control my hormones---- so needless to say I will not be taking anything besides my Lamictal. I experience the memory loss, inability to finish sentences or to find the words needed to make a sentence. My vision is getting blurred and I don't think it is my eye makeup remover etc. My hands shake a lot and it is embarrassing. My skin is blochy and I seem to be getting more age spots but from what I am reading it may be the medicine making my skin sensitive to sun...and me being too lazy to put oon sunscreen. The more I read about this stuff the more I want off of it. I think I am taking too much. I have a new doctor and I hope we'll figure this out together.

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