I can't tell if it's the Lodrane 24 D or the Nasex, as they were prescribed together and both are 24 hour drugs. About the time the good effects began to wear off and I became a little congested, after about 14 hours, I had a bad asthma attack which lasted til after 4am. When I woke up at 4am I had a very bad headache, slightly to the side of the forehead. It felt very much like a migraine. I took two advil and now at 8:40am the headache is better, but still slightly there and I feel generally blah. I haven't taken anything yet today.