I took Prilosec last night because my throat has been hurting and a friend suggested that I take the Prilosec to see if the pain might be reflux. I could not get out of bed this morning. I was ready to go get a mono test because of total fatigue and the sore throat but I am going to wait after reading these posts. Prilosec is the only thing that I have done differently. I also have a LOT of gas. I can't be sure if Prilosec caused the problems but I won't take the risk and take it again.