Well I have never been on medication for depression. I went to the doctor and he called it mild depression. I also wanted to quit smoking, so he prescribed me Budeprion XL, I never even thought that I had depression, I was just fine. I have been taking this medicine for a couple of weeks now and I can't sleep, I feel jittery like I've drank 2 pots of coffee, my ears ring loudly, I feel strange after I'm done eating, I almost feel like a numbness throughout my body, and my hands and feet sweat like crazy, but I'm cold at the same time and have to have a blanket on me. I have not experienced the joint pain, a little nausea. I think it's time to call the doctor!!!