Those discontinuing Effexor should ONLY proceed with doctor supervision. I weaned myself off Effexor after a five year therapy and I spent thirteen weeks with side effects which kept me home unable to do much at all. Some side effects are shocking sensations in the head, dizziness, agitation, moody or violent behavoir, among others.I still have some recurring problems after seven months, none of which are related to depression. In my opinion, this is a very dangerous drug for some patients.