I am a 44 year-old woman. I have been taking Topamax for 13 years! I take 100mg at bedtime (would NEVER take it during the DAY--that's ASKING for sedation). I take it along with 400mg of Wellbutrin & 30mg of Lexapro!!! I've taken various doses over the years. It was initially prescribed as a mood-stabilizer for my bi-polar II, and so happened to control my migraines. Happy Days!
When I FIRST took Topamax I remember having the strange feeling of small miscroscopic "fish" (or something) swimming under my skin, across my cheekbones and over the bridge of my nose. I never got a rash or anything. I did not feel that this passing side effect was anything I "couldn't deal with" as the medication stablized my mood without the HORRID side effects of Lithium, Depakote, Valproic Acid, etc!!!
All this time I have done very well and have NEVER had any health problems from the Topamax. I am VERY confused by folks who claim it gave them "mood swings"--as its effect is to make your mood stable!!! I don't understand how that could happen. Also this is a LOT of people having MAJOR effects from VERY low doses of the drug (50- 75mg mostly). Perhaps folks are medication sensitive OR something else is going on as well???