I'm glad to have found this website. I recently had a complete physical and blood work and everything is fine. So that leads me to believe the only thing that is causing my "issues" is the damn YAZ. I feel so angry, tired, mood swings easily, tired, irritable, and fatigued...did I mention tired. That's the worst of all of it for me. I've been on it for 7 months. I'd have to say around the 3rd or 4th month is when I started noticing how tired I feel. I'll be changing back to my old BC, ortho-tricyclen in hopes of improvement.