After about three weeks of taking the generic form of Welbutrin, I too broke out in a horrible case of hives. They started on my trunk and migrated all over my body. After two miserable days, I went to a redi med clinic late one night because I couldn't take the itching. The doctor said it wasn't the Wellbutrin, said it might be some type of allergic reaction to something else. They gave me steroid shot and sent me home with a steroid pack of pills to take over the course of a week. Three days later, no sign of the hives going away or becoming less irritated. Found some relief using the Target version of Gold Bond powder and benadryl every four hours. That's when I found this site. I immediately stopped taking the Wellbutrin and guess what? Twelve hours after I skipped my Wellbutrin dose, the hives were 80% gone. Today, 36 hours since the last Wellbutrin pill, the hives are almost all the way gone. This should certainly be listed as a possible side effect! I have never been so miserable in my life with itching!! If you have hives and are on Wellbutrin tell your doctor!