My fibromyalgia has totally flared since I had Mirena put in about 2 months ago. The fibro always was better when I was pregnant and since Mirena has increased progesterone (like pregnancy) that it wouldn't make it worse - maybe even better like pregnancy. But it's definitely worse and I'm really thinking it's because of the difference in hormones. When you are pregnant - estrogen is increased as well so maybe that difference is to blame. Who knows. I have also had more breakouts. No hair loss yet but major fibro problems (aches and pains, memory/cognitive problems, sensation of swelling/stiffness etc...). I am hoping if I have it out the flare will subside a bit. If I am still majorly flaring in a few weeks - I think I will have it out.