I think I have been on this the longest of anyone who has posted....18 years. Never really have had problems ( some of the following once in a blue moon; never all at once!) but I have 'em all now! Weight gain, depression, outlandish dreams (exhausting) and/or sleeplessness, diarrhea..almost daily and incapacitating, joint pain, ad infinitum. I am miserable. Have no insurance so I can't undergo anymore testing. I have persistent tachycardia of atrial origin....that's all I know. Having headaches and bet my BP is above normal. I hate this medicine but I know it's dangerous to just stop. Tried weaning off a couple of times but the tachycardia returns full steam, 160+ bpm, pretty fast. I am not much fun anymore that's for certain.