I started taking singular daily for two years now. i was diagnosed with seasonal Asthma and allergies of course. I was always getting colds and such. Singular did helped with those symptoms however now that I accidentally or luckily came across this web site I'm able to answer some of my questions. I feel very anxious, and always need to be physically doing something, then suddenly I have no energy or just feel rotten mainly at the end of the day. Since I also take Zoloft again due to Pre-menopausal symptoms and PDST I kept thinking it was the second condition and never gave a though about Singular. Unfortunately many of my symptoms have been blamed to my menopause and have tried many different alternatives with no help. Being a nurse though, sometimes I tend to rationalize my symptoms and try not to look into things. Never the less, reading all this information it really puts me to think about Singular. something that i have noticed is also my feeling of aggression, and thought irrationality. Ho! my God! I'm so shocked about all of this. I will go of Singular and plan to have a long discussion with my doctor. I will keep you all informed of any changes.