seemed to worsen my severe nausea. i took it 3 times to give it a chance to work, and again, i seemed worse. but I was having a very bad time of it, it's possible it just didn't work and I would have been worse anyway. But I had already been thru 5 straight days of severe nausea and 2 days of vomiting, and it was after this that I was given the Zofran ODT to try, and then again, seemed to feel worse.