Where to start? During a 7 day seige, the following "acceptable" side affects began to show up: tendonitis in the Achilles; cramps in the calves; soreness in the thighs and glutes; joint stiffness in knees; neck and arm pain; personality changes; and finally acne-like sores on the forehead. I was supposed to have 14 days of treatment, but didn't. I threw the medicine away, looked into homepathic remedies and finally cleared up the problem on my own. I'm sure this works for some...but not me. After stopping, all side affects disappeared except stiffness in my right calf. That lingered for about a month and then finally got better. I'll never knowingly take this stuff again.