I would just like to say that, even though I just started it, I love Microgestin(generic Loestrin). I'm finishing my first week of pills and things are already getting better. I had been on the shot for my 9 months when I couldn't take it anymore. In the week that I've started taking it, my depression has seemed to melt away. While on the shot I suffered from severe depression and mood swings. Also, I am no longer spotting after having spotted for almost the entire 3 months I had had my last shot. The only thing I noticed was that I had a little more discharge than I normally do and that my appetite may have gone up a little more..although I am trying to gain weight. Also I had some pain in my left shoulder and left leg? I don't know if it was related to the pill though. Just so you know, the shot makes you eat like a pig. I gained almost 15 pounds over the course of 9 months. I started out 5'7 105. I'm now 5'7 118. The shot also gives you hot flashes. Terrible terrible hot flashes.